Ebola Hemorrhagic Fever: Recent Update On Disease Status, Current Therapies And Advances In Treatment

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Published: November 2, 2017
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Authors

  • Jaskaran SinghChitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India
  • Thapa KomalChitkara College of Pharmacy, Chitkara University, Rajpura, Punjab-140401
  • Sandeep AroraChitkara College of Pharmacy, Chitkara University, Rajpura, Punjab-140401
  • Amarjot KaurChitkara College of Pharmacy, Chitkara University, Rajpura, Punjab-140401
  • Thakur Gurjeet SinghChitkara College of Pharmacy, Chitkara University, Rajpura, Punjab-140401
DOI Number
https://doi.org/10.15415/jptrm.2017.52013
Keywords
Filovirus, Ebola, Single-stranded ribonucleic acid, GRADE, vaccines, rVSV-EBOV, Favipiravir, ZMapp

Abstract

Swiftly growing viruses are a major intimidation to human health. Such viruses are extremely pathogenic like Ebola virus, influenza virus, HIV virus, Zika virus etc . Ebola virus, a type of Filovirus, is an extremely infectious, single-stranded ribonucleic acid virus that infects both humans and apes, prompting acute fever with hemorrhagic syndrome. The high infectivity, severity and mortality of Ebola has plagued the world for the past fifty years with its first outbreak in 1976 in Marburg, Germany, and Frankfurt along with Belgrade and Serbia. The world has perceived about 28,000 cases and over 11,000 losses. The high lethality of Ebola makes it a candidate for use in bioterrorism thereby arising more concern. New guidelines have been framed for providing best possible care to the patients suffering from Ebola virus i.e Grading of Recommendation Assessment, Development And Evaluation (GRADE) methodology to develop evidence-based strategy for the treatment in future outbreak of Ebola virus. No drugs have been approved, while many potent drugs like rVSV-EBOV, Favipiravir, ZMapp are on clinical test for human safety. In this review we will discover and discuss perspective aspects that lead to the evolution of different Ebola variants as well as advances in various drugs and vaccines for treatment of the disease.

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How to Cite

Jaskaran Singh, Thapa Komal, Sandeep Arora, Amarjot Kaur, Thakur Gurjeet Singh. Ebola Hemorrhagic Fever: Recent Update On Disease Status, Current Therapies And Advances In Treatment. J. Pharm. Technol. Res. Manag.. 2017, 05, 217-234
Ebola Hemorrhagic Fever: Recent Update On Disease Status, Current Therapies And Advances In Treatment

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Articles in Journal of Pharmaceutical Technology, Research and Management (J. Pharm. Tech. Res. Management) by Chitkara University Publications are Open Access articles that are published with licensed under a Creative Commons Attribution- CC-BY 4.0 International License. Based on a work at https://jptrm.chitkara.edu.in/. This license permits one to use, remix, tweak and reproduction in any medium, even commercially provided one give credit for the original creation.

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Journal of Pharmaceutical Technology, Research and Management by Chitkara University Publications is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://jptrm.chitkara.edu.in//

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The Journal of Pharmaceutical Technology, Research and Management is a peer-reviewed, refereed, bi-annual open-access journal of "Chitkara University Publications".  ISSN (p):2321-2217, ISSN (e): 2321-2225, RNI No.: CHAENG/2013/50088, Journal's DOI: https://doi.org/10.15415/jptrm

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