Diabetic Retinopathy: An Insight into Clinical Features, Therapeutic Approaches, and Implications

Published: May 7, 2021

Authors

  • Rupinder Kaur
  • Rithik, Kirti
  • Suman Baishnab
  • Shareen Singh
Keywords
Diabetes, Diabetic Retinopathy (DR), Vascular Endothelial Growth Factor (VEGF), Nutraceuticals, Carotenoids

Abstract

Background: Diabetes mellitus is a metabolic disorder that affects the heart, brain, eye, and other organs. Diabetic microvascular complications includes retinopathy, nephropathy, and neuropathy. Diabetic retinopathy is a multifactorial disease that develops as a consequence of microvascularcom plications, which causes damage to the retina by damaging the ocular fundus which further leads to visual loss.

Purpose: Pharmacological and non-pharmacological treatment works to prevent, delay or reduce vision loss. Non-pharmacological treatment include nutraceuticals (they have anti-inflammatory and antioxidant property) and pharmacological treatment includes anti-VEGF agents, corticosteroids, and specific moieties. Treatment with nutraceuticals in the early stages of diabetic retinopathy could be a viable option for intervening before the disease progresses.

Conclusion: This review briefly elucidates the emerging condition of diabetic retinopathy from epidemiological, pathophysiological, and therapeutic aspects including the emerging uses of nutraceuticals in diabetic retinopathy. If we control glucose and blood pressure levels in diabetic patients, it may halt the progression and development of diabetic retinopathy.

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How to Cite

Rupinder Kaur, Rithik, Kirti, Suman Baishnab and Shareen Singh. Diabetic Retinopathy: An Insight into Clinical Features, Therapeutic Approaches, and Implications. J. Pharm. Technol. Res. Manag.. 2021, 09, 17-27
Diabetic Retinopathy: An Insight into Clinical Features, Therapeutic Approaches, and Implications

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