Low Dose Aspirin as Prophylaxis Reduces the Incidence of Preeclampsia in Women at High Risk – A Review

Published: November 8, 2021

Authors

  • Riya M Cherian
  • Parminder Nain
  • Sanjana Mehta
  • Samrat Chauhan
  • Jaspreet Kaur
Keywords
Preeclampsia, Hypertension, Pregnancy, Aspirin

Abstract

Only pregnant women are susceptible to preeclampsia, a disorder that raises blood pressure and results in proteinuria, edema, or both. Although aspirin is not widely used due to safety and efficacy concerns, it is thought that high-risk pregnant women who take low doses of aspirin can avoid preeclampsia. Several clinical studies are been out on high-risk female patients to prevent preeclampsia with low dose aspirin (60-150 mg). Using a combination of keywords, the literature database that is available on multiple peer-reviewed national and international journals was searched electronically. Between 8 and 28 weeks of gestation, aspirin 100 mg or 150 mg was given together with a placebo to high-risk pregnant women in 11 RCTs. According to the existing research, preeclampsia and its associated foetal and maternal problems can be prevented or when high-risk pregnant women are given low-dose aspirin between 12 and 28 weeks of gestation, especially at night, the risk is decreased.

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How to Cite

Riya M Cherian, Parminder Nain, Sanjana Mehta, Samrat Chauhan and Jaspreet Kaur. Low Dose Aspirin as Prophylaxis Reduces the Incidence of Preeclampsia in Women at High Risk – A Review. J. Pharm. Technol. Res. Manag.. 2021, 09, 99-107
Low Dose Aspirin as Prophylaxis Reduces the Incidence of Preeclampsia in Women at High Risk – A Review

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