Low Dose Aspirin as Prophylaxis Reduces the Incidence of Preeclampsia in Women at High Risk

1e416013186c20a17cb4f44 20230721020921344 chitu:chitu chitkarauniversitypublications@chitkara.edu.in WEB-FORM Journal of Pharmaceutical Technology, Research and Management JPTRM 23212217 23212225 10.15415/jptrm https://jptrm.chitkara.edu.in/ 11 08 2021 11 08 2021 9 2 10.15415/jptrm.2021.92 https://jptrm.chitkara.edu.in/2021/vol-9-no-02/ Low Dose Aspirin as Prophylaxis Reduces the Incidence of Preeclampsia in Women at High Risk – A Review Low Dose Aspirin as Prophylaxis Reduces the Incidence of Preeclampsia in Women at High Risk – A Review Department of Pharmacy Practice, M.M College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana, Haryana - 133207, India Riya M Cherian https://orcid.org/0000-0001-6654-3137 Parminder Nain https://orcid.org/0000-0003-4571-3306 Department of Pharmacy Practice, M.M College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana, Haryana - 133207, India Sanjana Mehta https://orcid.org/0000-0002-5517-4273 Chitkara College of Pharmacy, Chitkara University, Punjab-140401, India Samrat Chauhan https://orcid.org/0000-0003-4120-6534 Chitkara College of Pharmacy, Chitkara University, Punjab-140401, India Jaspreet Kaur https://orcid.org/0000-0002-7753-0486 Department of Pharmacy Practice, M.M College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana, Haryana - 133207, India Only pregnant women are susceptible to preeclampsia, a disorder that raises blood pressure and results in proteinuria, edema, or both. Although aspirin is not widely used due to safety and efficacy concerns, it is thought that high-risk pregnant women who take low doses of aspirin can avoid preeclampsia. Several clinical studies are been out on high-risk female patients to prevent preeclampsia with low dose aspirin (60-150 mg). Using a combination of keywords, the literature database that is available on multiple peer-reviewed national and international journals was searched electronically. Between 8 and 28 weeks of gestation, aspirin 100 mg or 150 mg was given together with a placebo to high-risk pregnant women in 11 RCTs. According to the existing research, preeclampsia and its associated foetal and maternal problems can be prevented or when high-risk pregnant women are given low-dose aspirin between 12 and 28 weeks of gestation, especially at night, the risk is decreased. 11 08 2021 11 08 2021 99 107 10.15415/jptrm.2021.92010 https://jptrm.chitkara.edu.in/2021/low-dose-aspirin-as-prophylaxis-reduces-the-incidence-of-preeclampsia-in-women-at-high-risk-a-review/