Systemic Review: Sexual Dysfunction in Women with type 2 Diabetes Mellitus

Published: November 2, 2018

Authors

  • Ravinder KumarChitkara College of Pharmacy, Chitkara University, Rajpura-140401, Patiala, Punjab, India
  • Diksha GeraChitkara College of Pharmacy, Chitkara University, Rajpura-140401, Patiala, Punjab, India
  • Govind AroraChitkara College of Pharmacy, Chitkara University, Rajpura-140401, Patiala, Punjab, India
  • Pratima K SyalChitkara College of Pharmacy, Chitkara University, Rajpura-140401, Patiala, Punjab, India
Keywords
Diabetes, hyperglycaemia, sexual dysfunction

Abstract

Diabetes would not just have a high blood glucose level in the individual body, yet these days diabetes likewise goes with numerous other organic issues like hypertension, feeble the myocardial layer working, sexual broke, and so on. These are some real issue which is these days joined by diabetes to a person’s body. Guys are for the most part being determined to have the sexual broke issue, guys, as well as experience a sexual broke issue. As similarly we may see less clinical examinations, including sexual broke issues looked for the sort two diabetic ladies. The primary goal of this article is to illuminate the situation that females proceed with much trouble with regards to the sexual broke Complication that might be physiological or neurotic if there should arise an occurrence of sorting two diabetes in ladies. It chiefly involves the useful extent of females like sexual drive, excitement, vaginal grease, Orgasm and general fulfilment space. Talking about the treatmentaccess of the ailment in the analyti way for it, Diabetes essentially hinders the sexual execution of Diabetic Women. Determinants of sexual ability incorporate age and extent of diabetes.

References

  • Wild, S., Roglic, G., Green, A., Sicree, R. and King, H. (2004). Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes care, 27(5), 1047–1053. https://doi.org/10.2337/diacare.27.5.1047
  • Dennerstein, L., Randolph, J., Taffe, J., Dudley, E. and Burger, H. (2002). Hormones, mood, sexuality, and the menopausal transition. Fertility and Sterility, 77, 42–48. https://doi.org/10.1016/S0015-0282(02)03001-7
  • Pontiroli, A. E., Cortelazzi, D. and Morabito, A. (2013). Female sexual dysfunction and diabetes: A systematic review and meta‐analysis. The journal of sexual medicine, 10(4), 1044–1051. https://doi.org/10.1111/jsm.12065
  • Enzlin, P., Mathieu, C., Van den Bruel, A., Vanderschueren, D. and Demyttenaere, K. (2003). Prevalence and predictors of sexual dysfunction in patients with type 1 diabetes. Diabetes care, 26(2), 409–414. https://doi.org/10.2337/diacare.26.2.409
  • Lehman P. T., Jacobs J. A. (2006). Etiology of diabetic impotence. J Urol 129, 291–294. Lehman, T. P. and Jacobs, J. A. (1983). Etiology of diabetic impotence. The Journal of urology, 129(2), 291–294. https://doi.org/10.1016/S0022-5347(17)52057-1
  • Li, H., Qi, T., Huang, Z. S., Ying, Y., Zhang, Y., Wang, B. and Chen, J. (2017). Relationship between gut microbiota and type 2 diabetic erectile dysfunction in Sprague-Dawley rats. Journal of Huazhong University of Science and Technology [Medical Sciences], 37(4), 523–530. https://doi.org/10.1007/s11596-017-1767-z
  • Buvat, J., Lemaire, A., Buvat-Herbaut, M., Guieu, J. D., Bailleul, J. P. and Fossati, P. (1985). Comparative investigations in 26 impotent and 26 nonimpotent diabetic patients. The Journal of urology, 133(1), 34–38. https://doi.org/10.1016/S0022-5347(17)48773-8
  • Kim, B. H. and Son, S. M. (2006). Mechanism of developing diabetic vascular complication by oxidative stress. Journal of Korean Endocrine Society, 21(6), 448–459.https://doi.org/10.3803/jkes.2006.21.6.448
  • Skrha, J. (2003). Pathogenesis of angiopathy in diabetes. Acta diabetologica, 40(2), s324–s329. https://doi.org/10.1007/s00592-003-0113-z
  • Orasanu, G. and Plutzky, J. (2009). The pathologic continuum of diabetic vascular disease. Journal of the American College of Cardiology, 53(5 Supplement), S35–S42. https://doi.org/10.1016/j.jacc.2008.09.055
  • Doumas, M., Tsiodras, S., Tsakiris, A., Douma, S., Chounta, A., Papadopoulos, A. and Giamarellou, H. (2006). Female sexual dysfunction in essential hypertension: a common problem being uncovered. Journal of hypertension, 24(12), 2387–2392. https://doi.org/10.1097/01.hjh.0000251898.40002.5b
  • International Diabetes Federation (2012) Diabetes Atlas. Brussels, Belgium: International Diabetes Federation, 5th ed.
  • Owiredu, W. K., Amidu, N., Alidu, H., Sarpong, C. and Gyasi-Sarpong, C. K. (2011). Determinants of sexual dysfunction among clinically diagnosed diabetic patients. Reproductive Biology and Endocrinology, 9(1), 70. https://doi.org/10.1186/1477-7827-9-70
  • Basson, R., Berman, J., Burnett, A., Derogatis, L., Ferguson, D., Fourcroy, J.,& Leiblum, S. (2000). Report of the international consensus development conference on female sexual dysfunction: definitions and classifications. The Journal of urology, 163(3), 888–893. https://doi.org/10.1016/S0022-5347(05)67828-7
  • American Psychiatric Association (2013). Highlights of changes from DSM-IV to DSM-5. In: Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Arlington, VA: American Psychiatric Association.
  • Veronelli, A., Mauri, C., Zecchini, B., Peca, M. G., Turri, O., Valitutti, M. T.,& Pontiroli, A. E. (2009). Sexual dysfunction is frequent in premenopausal women with diabetes, obesity, and hypothyroidism, and correlates with markers of increased cardiovascular risk. A preliminary report. The journal of sexual medicine, 6(6), 1561–1568. https://doi.org/10.1111/j.1743-6109.2009.01242.x
  • Khalilzadeh, E. M. A. D., Hazrati, R. E. Z. A., Vafaie Sayah, G. and Hasannejad, H. A. M. I. D. E. H. (2015). Opioidergic and cholinergic but not nitric oxide pathways are involved in antinociceptive activity of Vitex agnus-castus essential oil in the acute trigeminal model of pain in rat. Asian J Pharm Clin Res, 8(1), 283–286.
  • Esposito, K., Ciotola, M., Marfella, R., Di Tommaso, D., Cobellis, L. and Giugliano, D. (2005). Sexual dysfunction in women with the metabolic syndrome. Diabetes care, 28(3), 756–756. https://doi.org/10.2337/diacare.28.3.756
  • Martelli, V., Valisella, S., Moscatiello, S., Matteucci, C., Lantadilla, C., Costantino, A. and Meriggiola, M. C. (2012). Prevalence of sexual dysfunction among postmenopausal women with and without metabolic syndrome. The journal of sexual medicine, 9(2), 434–441. https://doi.org/10.1111/j.1743-6109.2011.02517.x
  • Enzlin, P., Mathieu, C., Van den Bruel, A., Bosteels, J., Vanderschueren, D. and Demyttenaere, K. (2002). Sexual dysfunction in women with type 1 diabetes: a controlled study. Diabetes care, 25(4), 672–677. https://doi.org/10.2337/diacare.25.4.672
  • Mezones-Holguin, E., Blümel, J. E., Huezo, M.,Vargas, R., Castro, J., Córdova, W. and Castelo- Branco, C. (2008). Impact of diabetes mellitus on the sexuality of Peruvian postmenopausal. Gynecological Endocrinology, 24(8), 470–474. https://doi.org/10.1080/09513590802273749
  • Konuru, V., Sangam, K., Mohammed, A.,Kanneganti, S. (2017). Evaluation of Pharmacoeconomic Direct Cost In Diabetes Patients. Ashian journal od pharmaceutical and clinical research, 10(4), 38–40. https://doi.org/10.22159/ajpcr.2017.v10i4.8510
  • Leedom, L., Feldman, M., Procci, W. and Zeidler, A. (1991). Symptoms of sexual dysfunction and depression in diabetic women. Journal of Diabetic Complications, 5(1), 38–41. https://doi.org/10.1016/0891-6632(91)90009-E
  • Newman, A. S. and Bertelson, A. D. (1986). Sexual dysfunction in diabetic women. Journal of behavioral medicine, 9(3), 261–270. https://doi.org/10.1007/BF00844773
  • Bitzer, J. and Alder, J. (2009). Diabetes and female sexual health. Women’s Health, 5(6), 629–636. https://doi.org/10.2217/WHE.09.58
  • Bond, D. S., Vithiananthan, S., Leahey, T. M., Thomas, J. G., Sax, H. C., Pohl, D. and Wing, R. R. (2009). Prevalence and degree of sexual dysfunction in a sample of women seeking bariatric surgery. Surgery for Obesity and Related Diseases, 5(6), 698–704. https://doi.org/10.1016/j.soard.2009.07.004
  • Basson, R., Berman, J., Burnett, A., Derogatis, L., Ferguson, D., Fourcroy, J. and Leiblum, S. (2000). Report of the international consensus development conference on female sexual dysfunction: definitions and classifications. The Journal of urology, 163(3), 888–893. https://doi.org/10.1016/S0022-5347(05)67828-7
  • Lindau, S. T., Schumm, L. P., Laumann, E. O., Levinson, W., O’muircheartaigh, C. A. and Waite, L. J. (2007). A study of sexuality and health among older adults in the United States. New England Journal of Medicine, 357(8), 762–774. https://doi.org/10.1056/NEJMoa067423
  • Eyada, M. and Atwa, M. (2007). Sexual function in female patients with unstable angina or non-STelevation myocardial infarction. The journal of sexual medicine, 4(5), 1373–1380. https://doi.org/10.1111/j.1743-6109.2007.00473.x
  • Muharam, R., Budiman, B., Rachman, I. A., Nirmalasari, R. A. (2016). Effect of daidzen 120 mg supllimentation to menopausal symptoms and quality of life in non- equal producers women. Asian journal clin Res, 9(3), 37–40. https://doi.org/10.22159/ajpcr.2016.v9s3.14023
  • Lewis, R. W., Fugl‐Meyer, K. S., Corona, G., Hayes, R. D., Laumann, E. O., Moreira Jr, E. D. and Segraves, T. (2010). Definitions/epidemiology/risk factors for sexual dysfunction. The journal of sexual medicine, 7(4pt2), 1598–1607. https://doi.org/10.1111/j.1743-6109.2010.01778.x
  • Peng, Y. S., Chiang, C. K., Kao, T. W., Hung, K. Y., Lu, C. S., Chiang, S. S. and Lien, Y. R. (2005). Sexual dysfunction in female hemodialysis patients: a multicenter study. Kidney international, 68(2), 760–765. https://doi.org/10.1016/S0085-2538(15)50896-X
  • Bhasin, S., Enzlin, P., Coviello, A. and Basson, R. (2007). Sexual dysfunction in men and women with endocrine disorders. The Lancet, 369(9561), 597–611. https://doi.org/10.1016/S0140-6736(07)60280-3
  • Maiorino, M. I., Bellastella, G. and Esposito, K. (2014). Diabetes and sexual dysfunction: current perspectives. Diabetes, metabolic syndrome and obesity: targets and therapy, 7, 95.
  • Park, K., Ahn, K., Chang, J. S., Lee, S. E., Ryu, S. B. and Park, Y. I. (2002). Diabetes induced alteration of clitoral hemodynamics and structure in the rabbit. The Journal of urology, 168(3), 1269–1272. https://doi.org/10.1016/S0022-5347(05)64638-1
  • Feldhaus-Dahir, M. (2009). The causes and prevalence of hypoactive sexual desire disorder: part I. Urologic nursing, 29(4), 259.
  • Patil S, V., Mandare A, P.,Pandurang G. B. (2017). Study Of Total Cholesterol (Tc), Triacylglycerols (Tg), High Density Lipoprotein Cholesterol (Hdl-C) In Type II Diabetes Mellitus. Asian j Pharma clin Res, 10(2),116–118. https://doi.org/10.22159/ajpcr.2017.v10i2.14535
  • Bargiota, A., Dimitropoulos, K., Tzortzis, V., Koukoulis, G. N. (2011). Sexual dysfunction in diabetic women. HORMONES, 10(3), 196–06 https://doi.org/10.14310/horm.2002.1309
  • Duby, J. J., Campbell, R. K., Setter, S. M. and Rasmussen, K. A. (2004). Diabetic neuropathy: an intensive review. American Journal of Health-System Pharmacy, 61(2), 160–173.
  • Brown, J. S., Wessells, H., Chancellor, M. B., Howards, S. S., Stamm, W. E., Stapleton, A. E. and McVary, K. T. (2005). Urologic complications of diabetes. Diabetes care, 28(1), 177–185. https://doi.org/10.2337/diacare.28.1.177
  • Schram, M. T., Baan, C. A. and Pouwer, F. (2009). Depression and quality of life in patients with diabetes: a systematic review from the European depression in diabetes (EDID) research consortium. Current diabetes reviews, 5(2), 112–119. https://doi.org/10.2174/157339909788166828
  • Enzlin, P., Rosen, R., Wiegel, M., Brown, J., Wessells, H., Gatcomb, P. and Cleary, P. A. (2009). Sexual dysfunction in women with type 1 diabetes: longterm findings from the DCCT/EDIC study cohort. Diabetes care, 32(5), 780–785. https://doi.org/10.2337/dc08-1164
  • Enzlin, P., Mathieu, C., Van den Bruel, A., Vanderschueren, D. and Demyttenaere, K. (2003). Prevalence and predictors of sexual dysfunction in patients with type 1 diabetes. Diabetes care, 26(2), 409–414. https://doi.org/10.2337/diacare.26.2.409
  • Kumar Patnaik, S., Haritha, P., Rao P R. (2017). Erectile Dysfunaction and its pharmacology y: An overview, Asian J Pharma clin Res, 10(2), 17–23.
  • Rockliffe-Fidler, C. and Kiemle, G. (2003). Sexualfunction in diabetic women: A psychological perspective. Sexual and Relationship Therapy, 18(2), 143–159. https://doi.org/10.1080/1468199031000099415
  • Ogbera, A. O., Chinenye, S., Akinlade, A., Eregie, A. and Awobusuyi, J. (2009). Frequency and correlates of sexual dysfunction in women with diabetes mellitus. The journal of sexual medicine, 6(12), 3401–3406. https://doi.org/10.1111/j.1743-6109.2009.01396.x
  • Fugl-Meyer, A. and Sjogren, K. (1999). Sexual disabilities, problems and satisfaction in 18-74 year old Swedes. Scand J Sexol, 2, 79.
  • B Basson, R. (2005). Women’s sexual dysfunction:revised and expanded definitions. Canadian Medical Association Journal, 172(10), 1327–1333. https://doi.org/10.1503/cmaj.1020174
  • Bąk, E., Marcisz, C., Krzemińska, S., Dobrzyn-Matusiak, D., Foltyn, A. and Drosdzol-Cop, A. (2017). Relationships of sexual dysfunction with depression and acceptance of illness in women and men with type 2 diabetes mellitus. International journal of environmental research and public health, 14(9), 1073. https://doi.org/10.3390/ijerph14091073
  • Elyasi, F., Kashi, Z., Tasfieh, B., Bahar, A. and Khademloo, M. (2015). Sexual dysfunction in women with type 2 diabetes mellitus. Iranian journal of medical sciences, 40(3), 206.

How to Cite

Ravinder Kumar, Diksha Gera, Govind Arora, Pratima K Syal. Systemic Review: Sexual Dysfunction in Women with type 2 Diabetes Mellitus. J. Pharm. Technol. Res. Manag.. 2018, 06, 143-151
Systemic Review: Sexual Dysfunction in Women with type 2 Diabetes Mellitus

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