The Impact of Maternal Obesity on the Development and Outcomes of Congenital Masses: A Review
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2024,
Vol. 12 No. 01 > The Impact of Maternal Obesity on the Development and Outcomes of Congenital Masses: A Review
Published: April 20, 2024
Authors
Sarita Jangra, Amit Sharma, Thakur Gurjeet Singh, Bhavesh Dharmani, Tanya Sood, Kritika Sharma, and Bhupinder Bhyan, Yousef Saeed Alqarni, and Fahad Thabet Alsulami
Keywords
Obesity, Malformation, Pregnancy obesity, Congenital defects, Paediatric neoplasm, Maternal obesity, Congenital anomalies, Paediatric neoplasms, Still birth
Abstract
Background: The global prevalence of obesity has risen sharply, including among pregnant women, contributing to a significant increase in obstetric complications and adverse birth outcomes. One such concern is the development of congenital anomalies, which include cystic, solid, or vascular malformations. These anomalies are influenced by maternal factors such as pre-pregnancy malnutrition, inadequate folic acid intake, iodine deficiency, consanguineous marriages, insufficient immunization, and exposure to teratogens like alcohol. Addressing the high morbidity associated with these abnormalities requires a deep understanding of their anatomical and etiological factors.
Purpose: This review aims to examine the impact of maternal obesity on the development and outcomes of congenital masses. It seeks to identify mechanisms underlying these malformations, assess their prevalence, and explore strategies for prevention and management.
Method: A comprehensive literature review was conducted, focusing on studies that link maternal obesity with congenital anomalies. Relevant articles were identified from databases such as PubMed, Scopus, and Web of Science using keywords like “maternal obesity,” “congenital masses,” “foetal malformations,” and “pregnancy outcomes.”
Results: Maternal obesity was associated with an increased risk of congenital anomalies due to factors such as altered metabolic states, inflammation, and suboptimal nutrient levels. Early diagnosis and intervention were identified as critical for improving outcomes.
Conclusion: Maternal obesity significantly impacts the development and outcomes of congenital masses. Effective prevention strategies, such as nutritional counselling, obesity management, and early screening programs, are essential to mitigate these risks and improve maternal and neonatal health outcomes.
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How to Cite
Sarita Jangra, Amit Sharma, Thakur Gurjeet Singh, Bhavesh Dharmani, Tanya Sood, Kritika Sharma, and Bhupinder Bhyan, Yousef Saeed Alqarni, and Fahad Thabet Alsulami. The Impact of Maternal Obesity on the Development and Outcomes of Congenital Masses: A Review.
J. Pharm. Technol. Res. Manag.. 2024, 12, 62-69
