Dementia: An Overview

Abstract

Dementia is a neurodegenerative disorder characterized by progressive and continuous loss of cognitive functions. The neuropsychiatric symptoms include apathy; agitation and depression. As the disorder progresses, the patient gradually becomes dependent on others to perform routine daily activities. Various underlying diseases or disorders are the root cause of the syndrome of dementia. Each of these disorder or disease is characterized by a specific signs and symptoms in combination with a presumed underlying neuropathology. Alzheimer’s disease is the most prevalent cause of dementia. The second most prevalent cause is vascular dementia. In this review, the clinical types, pathophysiology and pharmacotherapy is summarized.

  • Page Number : 29-45
  • Keywords
    Amnesia, Alzheimer’s disease, Cognition, Dementia, Memory
  • DOI Number
    10.15415/jptrm.2014.21003
  • Authors
    • Nitin BansalDepartment of Pharmacology, ASBASJSM College of Pharmacy, BELA (Ropar) Punjab-140111, India
    • Milind ParleDepartment of Pharmaceutical Sciences, Guru Jambhwshawar University of Science & Technology, Hisar, Haryana-125001, India

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  • Published Date : 2014-05-20