Inhibition of Formalin Induced Paw Edema in Rats by Various Fractions/Extracts of Bryophyllum pinnatum

Authors

  • R. K. Gupta Babu Banarsi Das National Institute of Technology and Management, Lucknow, Uttar Pradesh-227108, India
  • M. Lohani Department of Biotechnology, Integral University, Kursi Road, Lucknow, Uttar Pradesh-226021, India
  • R. Vishwakarma Arya Collage of Pharmacy, RIICO Industrial Area, Kukas, Jaipur, Rajasthan-302028, India

DOI:

https://doi.org/10.15415/jptrm.2019.72008

Keywords:

Anti-inflammatory, Formalin, Bryophyllum, pinnatum

Abstract

Traditionally, Bryophyllum pinnatum is used in the management of arthritis and inflammatory diseases. However, B. pinnatum has not been analysed previously for anti-inflammatory activity. Hence, this study is designed to determine the anti-inflammatory effects of various fractions of B. pinnatum leaf extract using rat model of formalin-induced paw edema. Treatment with various fractions showed marked decrease in formalin-induced paw volume and edema in rats. The results of BPAAF treatment were comparable to standard drug, diclofenac. These results indicate that B. pinnatum could be developed as ant-inflammatory drug after further studies.

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References

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Published

2019-11-05

How to Cite

R. K. Gupta, M. Lohani, & R. Vishwakarma. (2019). Inhibition of Formalin Induced Paw Edema in Rats by Various Fractions/Extracts of Bryophyllum pinnatum. Journal of Pharmaceutical Technology, Research and Management, 7(2), 63–66. https://doi.org/10.15415/jptrm.2019.72008

Issue

Vol. 7 No. 2 (2019)

Section

Articles

License

Articles in Journal of Pharmaceutical Technology, Research And Management (J. Pharm. Technol. Res. Manag.) by Chitkara University Publications are Open Access articles that are published with licensed under a Creative Commons Attribution- CC-BY 4.0 International License. Based on a work at https://jptrm.chitkara.edu.in. This license permits one to use, remix, tweak and reproduction in any medium, even commercially provided one give credit for the original creation.

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Creative Commons License Journal of Pharmaceutical Technology, Research And Management by Chitkara University Publications is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://jptrm.chitkara.edu.in
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