JPTRM

An Insight on Analytical Profile on Bisoprolol Fumarate – A Selective Beta-1 Adrenoreceptor Blocker

Ajinkya G. Dhandar, Suraj R. Chaudhari, Saurabh B. Ganorkar, Amod S. Patil, Sanjay J. Surana and Atul A. Shirkhedkar

KEYWORDS

BF; Bioanalytical; UPLC/LC-MS; capillary electrophoresis; impurity profile

PUBLISHED DATE November 2017
PUBLISHER The Author(s) 2017. This article is published with open access at www.chitkara.edu.in/publications
ABSTRACT

BF is Beta-adreno receptor antagonist and used as an Anti- Hypertensive Drug. BF gives the blocking action on β1-adrenergic receptors in the heart and vascular smooth muscle. The present review compiles the various approaches implemented for quantification of BF in bulk drug, pharmaceutical matrix and biological fluid. This review represents more than 50 analytical methods which include capillary electrophoresis, HPLC, HPTLC, UV-Spectroscopy, UPLC, impurity profiling and electrochemical methods implemented for estimation of BF as a single component as well as in multicomponent.

Page(s) 185–216
URL http://dspace.chitkara.edu.in/jspui/bitstream/123456789/669/1/JPTRM%205-2-5.pdf
ISSN Print : 2321-2217, Online : 2321-2225
DOI 10.15415/jptrm.2017.52012
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